Warnings & Recalls for Inderal
Black Box Warning
Inderal | Propranolol has an attached “black box” warning to it, advising that there have been reports of exacerbation of angina and heart attacks after the abrupt discontinuation of
Inderal | Propranolol. When a discontinuation of an
Inderal | Propranolol regimen is being determined, always consult your doctor to see what methods best suit you and your condition. Dosage should be reduced gradually in the duration of at least a few weeks. If the patient is starting to get symptoms of withdrawals from this medication that exacerbates angina, reinstitution of
Inderal | Propranolol is advised. Always consult with a doctor or physician before discontinuation.
Contraindications
Inderal | Propranolol has contraindications attached to it that hinder a patient’s ability to take this drug, such as:
- Bronchial asthma
- Cardiogenic shock
- 2nd or 3rd degree heart block
- Hypersensitivity to propranolol hydrochloride
- Sick sinus syndrome
- Sinus bradycardia
Who Should Not Take This Drug
The following patients should not take
Inderal | Propranolol:
- Patients with diabetes mellitus
- Patients with hyperthyroidism
- Patients with peripheral vascular disease
- Patients with Reynaud’s syndrome
- Patients with myasthenia gravis
Inderal | Propranolol has a pregnancy category rating of C by the FDA, meaning that there’s not an inherent risk to the mother or child, however upon conception it would be best to find a way to wean off of it.
Inderal Treatment and Use
Inderal | Propranolol is a drug whose classification is that of a beta blocker. This drug is prescribed to treat abnormal heart rhythms, hypertension, heart disease, pheochromocytoma (a tumor on a glad close to the kidneys), as well as certain types of tremors. Please refer to the “warnings and recalls” tab to inquire about this drug’s “black box” warning.
The official FDA-labeled indications for Inderal | Propranolol are for:
Non-FDA labeled indications for Inderal | Propranolol include:
How This Drug Works
The mechanism of action for Inderal | Propranolol is as a non-selective beta-blocker that works by reducing inotropic, chronotropic and vasodilator responses to certain beta-andrenergic stimulation by competing to bind to sites to receptors that are available. The way that Inderal | Propranolol controls hypertension, tremors and migraines isn’t understood. This drug is noted for being anti-arrhythmic, having anesthetic-like attributes as well as quinidine-like effects.
Dosage Information
The dosing of Inderal | Propranolol is relative to the specific condition of the patient and whether or not they’re correctly following the drug regimen.
- For angina, hypertension and tremor, the daily dose is up to 120mg-320mg per day
- For migraines, the daily dose is up to 160mg-240mg per day
- For hypothyroidism, arrhythmias and anxiety, the daily dose is up to 10mg-40mg 3-4 times a day
- For stage fright, 5-10mg before and after performance
