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Lisinopril, 2.96 / 5 (89 votes)

Lisinopril Side Effects

lisinopril packageLisinopril may cause uncommon but serious adverse side effects. If you experience any of the following symptoms, contact your doctor immediately:
  • Changes in heart rate or potentially a heart attack or muscle strength due to variations in potassium levels
  • Allergic reaction to angiotensin-converting enzyme inhibitor resulting in symptoms such as a swelling of the face, throat, tongue, hands, feet or ankles. This can lead to a more severe case of angioedema in which swelling of the dermis occurs and may even become fatal.
  • Jaundice, yellowing of the eyes and/or skin, darkened urine and a loss of appetite which could be signs of liver problems
  • Flu-like symptoms including a fever, chills or aches (without nausea or vomiting), coughing, sneezing or a runny nose
  • Syncope or faintness due to a drop in blood pressure caused by the medication
  • Decrease in urination or urinary tract infections
  • Anemia, or a low red blood cell count leading to a decrease in availability of oxygen
  • Transient ischemic attacks or a "mini stroke"
  • Women who are pregnant risk injury or even mortality to the fetus
  • Elderly patients risk an increase in renal dysfunction due to extremely low blood pressure cause by Lisinopril
Common side effects of using Lisinopril can include:
  • Depression
  • Dizziness
  • Stomach aches or diarrhea
  • Rashes or itchiness
  • Decrease in sexual aptitude
  • Weight loss or weight gain
  • Patti evans

    I was put on lisinopryl 10 months ago. When I presented with cough my provider took me off it. But then the cardiologist she sent me to put me back on it. So for at least 9 months I have been coughing till I gag and vomit. My origin provider took me off it yesterday. I’m mad though at how my health and quality of life has deteriorated over this year with that med.

    • HelenMarie

      Hi Patti, sorry for your experience, I recently have been prescribed this same med, I am interested to know how this med. affected you negatively.I appreciate any reply,

      • Patti evans

        Just seeing this Helen. It was a terrible cough.It’s a rare allergic reaction to the med. My primary realized it quickly took me off it,but then a cardiologist put me back on it. Seems it is the preferred med for high blood pressure. And somehow he didn’t get the note that I was allergic to it. Hope it worked for you. Hugs

    • connie

      The coughing has ruined my life and is on the verge of my guy leaving-after 6 years! I’m off it now but not much change! I am embarrassed to go anywhere because of the coughing ‘fits’! Keep going to doctor and she keeps trying new things, but only marginally better. I am 75 and feel this is going to shorten my life. I WAS still very active till this happened!!

      • Patti evans

        Just seeing this Connie. Mine put me on Losartan again for the HBPressure. And the cough went away in about 6 weeks. I still have a cough but not to the point of gaging and throwing up. Hope you got off it. Hugs

        • tinynot

          heya Patti, and others that may still be here, well i am off of everything but, Metropolol, and warphrin, i hope i am spelling that right. i am also for pain, talking Tramadal, is there anyone else here taking that also for pain? just wondering how if anything, is effecting them, and if it is helping at all. seems to be helping me, but sometimes seems to be making me very sleepy type of sensation, perhaps only ones taking it will have a clue as to what i mean, but. Tramadal to me seems to me a very weird drug, to say the least. to try and explain how it works and helps me is very difficult. seems to take the pain away, but it makes me feel weird, very hard to explain. [HOWARD]

          • Sandy P.

            Tramadol is a short term pain solution and shouldn’t be used for long term. My daughter-in-law just found this out after several Drs and many years of treatment for endometriosis. She’s now on a other med, low dose.
            As for lisinopril, my mom’s new primary took her off of it due to the cough. Mom has had 2 strokes, Afib, desperately needs a valve replacement plus much more. She’s stubborn and very hard to care for sometimes but she’s been both parents since I was 10. (Dad passed, massive heart attack) Research every pill that you’re given. It’s YOUR body and have the right to question everything they want to give you! Mom’s original heart doc was giving her meds for PANIC ATTACKS. She had Afib, they were causing episodes to double. Weaned her from all his meds, got a new Dr all is pretty good. Oh, warfarin and baby aspirin can be too much if you’re sensitive to meds in general. Good luck everyone and God bless.

          • Howard Ollman

            about the tramadol, doc says for the pain i have i very well may need to take it for rest of life. wby you say it needs to be only short term and not long term? i don’t understand, and it is my life and really need & want to know.
            thank you in advance
            Howard…. +7869250008

          • Howard Ollman

            oh ya, sorry about that, i pray your mom is doing better and she gets valve that she needs,
            thanks again

          • Merry Wana

            Sandy, how is your mom doing, better i hope. is she going to have that heart valve replaced, if you dont mind me asking. June/2015 is when i had mine done, the valve is a saint jude mitral valve, which valve is your mom having problems with. will pray for you and your mom.
            also, if you would, what is it with the tramadol, your daughter in law, why did she need to come off of it?
            what problem was it causing?
            Howard in miami FLA.

      • Deb S

        Try 65mg of iron daily – I had the same problem and the iron worked in a day or two. I was desperate and was reading everything I could to find a way to stop the coughing and choking.

    • Elaine Calabria

      OMG! That is ME! I am so glad you wrote this. I have had the cough but then started gagging. Thought I had some kind of ulcer or acid reflux even though I am already on a protonix!….Seriously gagging and coughing or just feeling like I am
      suddenly going to vomit after eating. But it ALL started with this drug. I am done!

  • debi gullo

    I was put on this medication also when i noticed the coughing, dizziness (i fell in the night going to the bathroom). and worst of all I developed phsiriosis all over my body. I am furious. I dont know who to be angry with my doctor or FDA. Doctors are so quick to put you on meds.

    • Patti evans

      Just seeing this Debi. Hope you got off it. My primary put me back on Lospartan for the HBP. That is working for me. That other crap was a nightmare. My primary realized the problem quickly, but the cardiologist she had sent me to put me back on it.

      • Patti evans

        I wish my primary had put it on my chart then that I was allergic to it. She has put it on now. But that drug took a year of my quality of life.

  • tiny

    is there still anyone following this post. my story is as follows: JUNE/5th/2015 i am now the proud owner of a saint jude mitral valve, saw my heart doc the other day and he stated that he had thought my heart numbers were not good enough, refraction or whatever they call it was 30-35. he put me on lisinopril 10mg every day. first question isnt that a bit much to start and perhaps the 2.5mg should have been indicated, just asking. i am now on metropolol, warfrin, digoxin, baby asprin. anyone else out there taking any of those others also at the same time while taking Lisinopril ?

  • Dian Flatt Lightner Long

    My doctor just put me on this and I was told about this by a family member that it’s not good my dose is 5mg what’s the alternative to this I don’t want to get sick from this I already have a cough from broncidus

    • Deb S

      Your cough could be from the drug is a side effect – I took the drug for 4 days didn’t sleep because of the cough and choking and tickle in my throat – it has been going on for 3 months! I read that an iron supplement would help and i started taking one 65 mg of iron and like magic I only cough and choke about 2-3 times a day. I also take lots of garlic oil. I don’t eat processed or canned food becasue of the salt content.

  • Jack G Simpson Jr

    The common side effects of Losartan are worse than Lisinopril and there’s more of them. There has to be a natural way to keep BP under control.

    • tiny

      my DOC’s say this is no the reason they are having me take Lisinopril, they claim i need it to make my heart work better, and get stronger. it seems to be working, but i dont really know for sure. The dose for me right now is half of a 50MG tab everyday. not sure what is going on, i seem to be having some side effects from something, sleeping pattern, thinking process seem to be effected and are some of the side effects. all in all i dont feel quite right but very difficult to explain.

      • Jack G Simpson Jr

        I’m sorry to hear you are having so much trouble. I’d go to another doctor and see what they say. Also, I seem to be on a really high dose. 100mg a day of losartan potassium. I have the cough, the pain in my side, the breathing difficulty when exerting. I am looking for a natural supplement to take so I can quit taking this thing.

        • tiny

          please if you find a NATURAL, please mention here, and detail all the info and whatever else you find out. i want to get off some of this crap so bad, i can feel it aint good for my body. but for right now i, like so many, have no choice. thank you

          • James Cox

            The easiest way to keep blood pressure under control is to use Lite Salt. It is half NaCl and half KCL. Drink lots of fluids and your kidneys will balance your electrolytes naturally. This will also stop muscle cramps. To jump start lowering your BP, do a DR. CLARK’S LIVER CLEANSE. Epsom salt relaxes blood vessels and the effects last 3 to 6 months. Good Luck!

          • Dee Bishop

            L-arginine and Chinese Skullcap. I take 1 of each in the morning and the skullcap again at night. Lisiniprin was doing nothing for me except make me confused and dizzy, tired and achy. I went from 145/90 to 118/69

          • Peterpanned

            Garlic will naturally drop your blood pressure quite a bit. Eat raw minced. 1 clove per day. Swear . Boom 100!

        • Pete

          Hibiscus tea, beetroot juice, dark chocolate to name a few. Lots of info out there on these and others.

        • Dee Bishop

          I started taking L-arginine and Chinese Skullcap supplements. After learning that Lisinipril isn’t so “safe” as I was led to believe. It was working anyway but now my blood pressure is normal. Down to 118/ 72 from 145/90.

          • tinynot

            awesome you have your bp under control, great news. my docs are telling me i need it to help my heart get stronger. i have now a saint jude mitral valve.

    • bobby dickey

      beets….stop all fast foods, processed foods..eat more fruits and vegetables…little sugar…exercise…no lisonopril…no metoprolol

  • exaag

    My wife went on Lisinopril after her heart surgery in November 2014. For the next year she had lengthy coughing attacks, dry heaves, could not sleep due to choking and coughing spells. Due to her heart and kidney issues the doctors kept giving her iron supplements and more drugs, but never once mentioned Lisinopril as the possible culprit. My son, a pharmacy tech in the U.S. Navy, noticed the Lisinopril prescription and immediately identified it as the cause. My wife’s doctor made a sarcastic reference to my son, but took her off Lisinopril 3 weeks ago. She was then hospitalized with pneumonia. The coughing attacks have stopped. It is incredible. She is actually sleeping at night.

  • Sue

    I was just told by a friend that Lisinopril can cause ITP which both her husband and my husband have been diagnosed with. Does anyone else know anything about this?

  • Homie’sMom

    The side affects of Lisinopril is life threating and has affected more than 427,000 people. I am one of them I was on 5mg, immediately started having breathing problems. Called ambulance, husband there telling me I was talking to him and the doctor when all of a sudden I stopped breathing. my face, tongue, throat, and tissues all swelled up. I was put on a ventilator and put in a medically induced coma with propofol. I spent 14 days in a coma, none of which I remember. I have a Tracheostomy scar, which was an emergency situation cause while trying to get me off the ventilator I stopped breathing each time(3). After I got out of Icu I was put on the medical icu floor. The Doctor’s determined that I had Angiedema due to Lisinopril. I went into the Hospital on May 29, 2014, and came home June 20th 2014. Imagine waking up thinking it was still May 29th, there stood some nurses, my husband and I could not talk. The nurse told me welcome back Ms. Malcolm you were in a coma for 14 days. I looked to my husband of 34 years he nodded his head yes and all I could do was cry. I had to have someone wash my butt and private parts, that was humiliating. I tried calling the nurse with the call button, how can I help you, ms Malcolm are you okay I could not talk. I got bed sores from them not turning me .I had to have speech therapy, occupational therapy, physical therapy in the hospital and then they came home with, me a nurse and a home health aid. I now suffer from PTSD and my memory is gone long term and short term .This is a very, very, dangerous drug and it needs to be taken off the market immediately.

  • apisxv

    URGENT. EXTREME DANGER. LISINOPRIL FROM LUPIN IS CRAP. The lisinopril (specifically from Lupin I hope; 20 MG reduced size tiny pill) issue may be very dangerous. Walgreens won’t assist in getting a replacement mfr but I found another that uses a different co. Not only is the lupin brand not bioequivalent, I think it may be the wrong active ingredient as it obviously causes the opposite effect from what is intended. I was headed to the hospital (severe chest pains & BP of 190/110) but now my chest pains have disappeared completely and my BP is back to normal. I’m going to have the tiny 1/2 sized Lupin 20mg lisinopril “parmachecked” by my attorneys. I notified FDA last Thursday and today. They seem clueless. My Walgreens doesn’t give a shit either. Thank God for my doctor and her clinic. Now back to 120/70 62 bpm thanks to different manufacturer.