Warnings & Recalls for Aloxi
Aloxi | Palonosetron Hydrochloride has the potential to be contraindicated in patients who’ve got the following symptoms and concerns:
- hypersensitivity to palonosetron hydrochloride, which is the active component of this drug
- concomitant use of apomorphine
Patients who are pregnant or nursing should consult their doctor before using Aloxi, as there have been no well-controlled studies over the side effects this medication can cause in unborn children.Patients who are under the age of 18 should seek advice from a doctor before taking Aloxi, as there have been no well-documented studies in younger patients.As of yet, Aloxi has not been recalled.
Aloxi Treatment and Use
Aloxi | Palonosetron Hydrochloride is a 5-HT3 receptor antagonist medication that is administered intrevenously 30 minutes before chemotherapy, or as a single capsule one hour before chemotherapy. Aloxi works by blocking the action of serotonin, which is a natural substance that can induce vomiting and nausea.
Aloxi is used to prevent nausea and vomiting that can occur within the 24-hour period after receiving surgery or chemotherapy, and actively works against the vomiting reflex and has little to no effect on other receptors. It is also used to prevent delayed nausea and vomiting that can occur within days after receiving certain chemotherapy regimens.
It is worth noting that it is the only drug of its classification to be approved by the FDA for the kind of treatment it provides. It is manufactured by the company Eisai Inc.
Side effects of chemotherapy
Aloxi helps patients undergoing chemotherapy by reducing the occurrence of nausea and vomiting. Patients often view these conditions as some of the most undesirable side effects of chemotherapy, and may even avoid chemotherapy treatment if they feel that these symptoms are too difficult to manage. Nausea and vomiting caused by chemotherapy can progressively worsen if not treated on the first day, making Aloxi vital.
Other side effects of chemotherapy include, but are not limited to:
- hair loss
- lowered immune system, which may lead to infection
- fatigue that is often related to anemia caused by treatment
- low platelet counts, leading to increased bleeding
If you are undergoing chemotherapy it is because your doctor believes that the benefit that this treatment will provide outweighs any negative side effects. If you have difficulty tolerating the side effects of chemotherapy treatment, do not be discouraged. Instead, speak with your doctor to find the best way to manage these side effects.
