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Signs of low blood sugar including (headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery)
Aches such as ongoing pain that begins in the upper left or middle part of the stomach but can spread to the back, or dull ache in the mid to lower back
Signs of allergic reaction such as swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs; difficulty breathing or swallowing; hives, rash, or itching
Changes in urination such as changes in the color, amount or frequency
Other side effects such as changes in appetite or digestion, hoarseness, excessive tiredness
Byetta Side Effects- Common
Gastrointestinal side effects such as nausea, vomiting, diarrhea, and indigestion
Nervous system side effects such as dizziness, headache and feeling jittery
Dermatologic side effects such as hair loss
General side effects including weakness and weight loss
Warnings & Recalls for Byetta
FDA Alerts
[8/18/2008]FDA received reports of 6 cases of hemorrhagic or necrotizing pancreatitis in patients taking Byetta in which all patients required hospitalization, two patients died and four patients were recovering at time of reporting.[10/16/2007]FDA reviewed 30 postmarketing reports of acute pancreatitis in patients taking Byetta (exenatide).Some patients have chosen to take legal action against the manufacturers of Byetta by filing a pancreatic cancer lawsuit for the damages they have suffered.
Family Planning Warnings
General Warnings
Patients are advised to tell their doctors if they have a history of any of the following conditions:
an allergy to exenatide, which is the active ingredient in Byetta, or any other medications
Kidney problems, including kidney failure
Diabetic ketoacidosis
Diabetic gastroparesis or other digestive tract condition
Pancreatitis
Interactions
Acetaminophen
Antibiotics
Lovastatin (Mevacor)
Oral Contraceptives
Warfarin (Coumadin, Jantoven)
Alcohol
Byetta Treatment and Use
What is Byetta?
Byetta | Exenatide, approved by the FDA in 2005, is prescribed in conjunction with diet and exercise to treat diabetes mellitus type 2.
How Byetta works
There are 5 mechanisms of response when it comes to the drug Byetta:
Byetta augments pancreas response in insulin secretion as a result of eating meals. The yield is usually the release of a higher and appropriate amount of insulin that assists in lowering the rise of blood sugar as a result of eating.
Byetta suppresses pancreatic release of glucagon as a response to eating, which in turn stops the liver from the overproduction of sugar when its not needed. This is turn prevents hyperglycemia.
Byetta assists in the slowing down of gastric emptying and thus decreases the rate in which glucose that’s derived from a meal enters into the bloodstream.
Byetta has a distinctly subtle yet prolonged effect which reduces appetite, to promote satiety through hypothalamic receptors.
Byetta reduces fat content of the liver.
Byetta Dosage
Byetta is injected in the thigh, abdomen or upper arm in 5 mcg doses, twice daily, at approximately one hour periods before each of the two main meals of the day. Byetta should not be administered after a meal. After one month of therapy, the dosage may be increased to 10 msg twice daily. As of 2012, a once-weekly injection has been approved under the name Bydureon.
Other Names for Byetta
Generic Name
Exenatide
Brand Name
Byetta
Bydureon
Lawsuits & Legal Information for Byetta
Byetta Lawsuit Updates
Current
Review: (July 2013) A Judicial Panel on Multi-District Litigation will meet in July to review the petition to consolidate Byetta, Januvia, Janumet and Victoza lawsuits into an MDL.
Lawsuit: (2013) More than 40 alleged Byetta pancreatic cancer lawsuits are pending in U.S. courts.
Future
Far Past
Lawsuit: (2007) The first known Byetta lawsuit was filed for insufficient knowledge on the risks of the medication.