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Didanosine Side Effects

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Serious Side Effects of Didanosine

  • liver damage which may cause side effects of itching, pain in the lower abdomen or back, upset stomach, vomiting, decrease in appetite, dark-colored urine, pale or clay-colored stools, and jaundice (yellowing of the skin or eyes)
  • bloating, enlargement of stomach, vomit the consistency of coffee grounds or coughing up blood
  • feeling anxious, agitated or nervous
  • difficulty sleeping (insomnia)
  • bowel problems which may result in severe diarrhea
  • inflammation of the neck or throat area
  • eye or vision changes: trouble seeing, sore or painful feelings in eye, seeing random flashes of light, trouble moving eyes
  • difficulty breathing, speaking or walking properly
  • numb or tingling sensations
  • new infection which may cause flu-like symptoms
  • bruising easily or abnormal bleeding
  • sores on the inside of the mouth
  • increase in heart rate
  • shaking or twitching (tremors)
  • rapid and unexplained decrease in weight
  • changes in menstruation
  • trouble having sex, or loss in desire to have sex (decreased libido)
  • appearing more pale than usual, weakness and feeling lightheaded
  • strong pain in the lower portion of the back and decrease in bowel function which may cause a loss of bladder control
  • lactic acidosis (excess lactic acid produced in the body) with the following side effects: weakness, numbness, muscle pain or aching, difficulty breathing, rapid or irregular heart beat, pain in the lower section of the abdomen, nausea accompanied by omiting, and feelings of dizziness, faintness or drowsiness
  • severe allergic reaciton: hives, rash, hoarseness, difficulty breathing, and swelling of the tongue, throat, mouth or face

Common Side Effects of Didanosine

  • headache or pain
  • rash
  • nausea
  • mild tinging or numbness
  • mild diarrhea
  • change in the distribution of fat around the body