Gadoteridol Side Effects
Severe Side Effects of Gadoteridol
- Gadoteridol may cause Nephrogenic Systemic Fibrosis in patients with renal impairment or renal failure.
- This drug and other gadolinium-based contrast agents may cause anaphylactic shock and other allergic reactions.
- If the patient has renal impairment, kidney failure or worsening of renal function may occur when taking Gadoteridol.
- Gadoteridol may cause cardiac arrest in patients with cardiovascular disease.
Common Side Effects of Gadoteridol
- Gadoteridol may cause Edema and swelling, hypertension, hypotension, tinnitus, or hives.
- Nervous system side effects include anxiety, vertigo, and seizures.
- Gadoteridol may cause vomiting, loose stools, drymouth, stomach cramps, and gum inflammation.
- Gadoteridol may cause decreased bladder control.
Warnings & Recalls for Gadoteridol
Black Box Warning for Gadoteridol
If the patient is not able to eliminate the drug or has renal impairment, Gadoteridol may cause
Nephrogenic Systemic Fibrosis, which can cause excess scar tissue of the skin, joints, eyes and internal organs. If the patient is suspected to have renal impairment, he or she should be screened before being injected with Gadoteridol.
Other Warnings for Gadoteridol
- Gadoteridol is meant for adults and children over 2.
- Gadoteridol is a pregnancy category class C drug and may be dangerous to take while pregnant. In lab rabbits receiving Gadoteridol, there was an increase in spontaneous abortions and premature births compared to the control group.
- Patients should inform their doctor if they have anemia or any kidney related problems.
Gadoteridol Treatment and Use
Gadoteridol | ProHance is an injectable MRI contrast agent used to help identify and diagnose lesions in the head, brain, spine, and neck. It is a gadolinium-based contrast agent. Recently, the FDA issued a black box warning on this class of contrast agents including MultiHance, ProHance, Omniscan, Optimark, and Magnevist. ProHance is the brand name of Gadoteridol and is manufactured by Bracco Diagnostics Inc.
What does Gadoteridol do?
Gadoteridol is injected to create a magnetic moment which enhances MRI scans and helps to better visualize the brain or spine for diagnostic purposes. Clincial trials have proved the drug to be efficacious. About 45% of the scans enhanced with Gadoteridol revealed more diagnostic information and around 8% of the diagnoses were changed due to scans with Gadoteridol.
Dosage
The usual dosage for Gadoteridol is 0.2 mL per 2.2 lbs of weight. Gadoteridol is available in 5, 10, 15, 17, and 20 mL vials.
Other Names for Gadoteridol
Brand Name
Generic
Lawsuits & Legal Information for Gadoteridol
Author:
Dru Watkins
Posted on Dec 28, 2012
