Gonal-F Side Effects
Serious Adverse Side Effects
Gonal –F | Follitropin Alfa Injection has some very serious adverse side effects associated with it, such as:
Common Adverse Side Effects
More common and less severe adverse side effects of this drug include:
- Gastrointestinal side effects such as abdominal pain and nausea
- Neurological side effects such as headache
- Respiratory side effects such as upper respiratory infections
It is worth noting that taking
Gonal –F | Follitropin Alfa Injection has often resulted in a patient bearing more than one child in her womb as a result of over-stimulation of the ovaries.
Warnings & Recalls for Gonal-F
Contraindications
Gonal –F | Follitropin Alfa Injection has contraindications to it that hinder a patient’s ability to be prescribed to it, such as:
- Abnormal vaginal bleeding
- High levels of follicle stimulating hormone (FSH) which indicates primary gonadal failure
- Hypersensitivity to the active ingredients in this drug, including FSH
- Patients who’ve had a pituitary tumor
- Patients who’ve had ovarian cysts
- Patients who are already pregnant
- Patients undergoing hormone therapy in regards to tumors of the reproductive tract
- Patients with uncontrolled thyroid dysfunctions
- Patients with uncontrolled adrenal dysfunctions
Who Should Not Take This Drug
Patients with or without pulmonary or vascular complications may suffer ovarian hyperstimulation syndrome as a result of taking this drug.
Gonal-F Treatment and Use
Gonal –F | Follitropin Alfa Injection is a fertility drug manufactured and produced by the drug company EMD, a subsidiary company of the pharmaceutical company Merck. It is indicated specifically for women desiring to conceive children who are facing difficulties doing so. As indicated, Gonal –F | Follitropin Alfa Injection is indicated for the inducing of ovulation and pregnancy in infertile patients in females whose cause of infertility is a functional matter and isn’t due to primary ovarian failure. It is also indicated for development of multiple follicles in an ovulatory patient participating in a special program that is sponsored by the drug company that manufactures, markets and produces Gonal –F | Follitropin Alfa Injection.
Another indication for this drug is that it is indicated for men who are having trouble with spermatogenesis in men with either primary or secondary hypogonadism, a condition where the male patient is having trouble with his sperm count and whose condition isn’t due to primary testicular failure.
It is worth noting that in the year 2009, the revenue for Gonal –F | Follitropin Alfa Injection was about $690 million.
How This Drug Works
Before going on a regimen of Gonal –F | Follitropin Alfa Injection, there are some assisted reproductive technology protocols that are a formality of this drug. This includes a pretreatment with gonadotropin-releasing hormone agonist in order to suppress pituitary releases of gonadotropins. Once this has been achieved, the patient’s physiology concentrations of gonadotropins are replaced with this drug. Gonal –F | Follitropin Alfa Injection stimulates follicle recruitment, growth and maturation. Gonal –F | Follitropin Alfa Injection’s ability to increase the fertility of women varies widely among many individuals. While the patient is on this drug, serum levels of the hormones necessary for a successful pregnancy are present in the body. After the discontinuation of Gonal –F | Follitropin Alfa Injection from a patient’s system, concentrations of the serum levels are diminished greatly, thus the patient goes back to a state where they are not able to conceive in the same capacity in comparison with the duration when they were using a regimen of Gonal –F | Follitropin Alfa Injection.