Warnings & Recalls for Jentadueto
Jentadueto Black Box Warning
Jentadueto may put you at risk for developing
lactic acidosis or serious
liver injury. Lactic acidosis occurs when lactic acid builds up in the bloodstream at unhealthy amounts due to an abnormal drop in oxygen levels; lactic acidosis may be serious and even deadly. Patients who are prone to
dehydration, frequently
drink alcohol, or have the following should be aware that they are more likely to develop this dangerous condition:
- liver disease
- kidney disease
- congestive heart failure
- any serious infections
See "
Side Effects" tab to find out more about
symptoms of lactic acidosis and contact your doctor immediately if you are suffering from any of the symptoms listed.
Jentadueto and Pregnancy
Jentadueto has been marked as an FDA
pregnancy Category B medication. Jentadueto has not been found to cause harm to the fetus when taken during pregnancy. It is
unknown if Jentadueto can pass through breast-milk and harm a nursing baby.
Do not breastfeed if you are taking Jentadueto. Let your doctor know if you are
pregnant or
planning on becoming pregnant before using Jentadueto as a treatment.
General Warnings
Patients who are in a state of
diabetic ketoacidosis (the body can no longer use sugars properly), are
allergic to Jentadueto, or have serious
kidney problems should
not take this medication.Let your healthcare provider know about
any of the following conditions you may have before using Jentadueto:
- liver disease
- a history of heart disease or heart attacks
- sepsis (when the body has a serious reaction to bacterial or germ infections)
- if you have ever had pancreatitis
- if you are an elderly patient and have not had a recent kidney function checkup
Let all healthcare providers know that you are taking Jentadueto. If you are having
surgery, let your doctor know in advance; you may be asked to stop using Jentadueto for a short period of time.
Jentadueto Treatment and Use
Jentadueto | Linagliptin and metformin is a dipeptidyl peptidase-4 (DPP-4) inhibitor and biguanide medication marketed by Eli and Lilly Company for treating type 2 diabetes. Jentadueto may be prescribed for:
- controlling high blood sugar levels
- preventing damage of the kidneys
- reducing the risk of vision loss, nerve damage, loss of limbs (arms or legs) or the inability to have sex
- decrease the risk of having a heart attack or stroke
Jentadueto is not a treatment for type 1 diabetes.
How Does Jentadueto Work?
Jentadueto works by increasing the production if incretins which are responsible for maintaining healthy blood sugar levels. Incretins produce insulin which helps in the breakdown of sugar, reduces the creation of sugar from the liver, and decreases sugar absorption in the body.
Jentadueto Dosage Information
Jentadueto comes in tablet form to be taken by mouth. Use only the amount prescribed to you by your doctor. Do not stop taking Jentadueto even if your symptoms are relieved and you feel well. Follow all instructions given to you by your doctor. To maintain your blood sugar levels, you may be asked to adhere to a strict diet, medicine and exercise plan.
As an initial dosage, Jentadueto is usually prescribed to be taken twice each day in 2.5 mg linagliptin/500 metformin HCl doses, once before lunch and before dinner. Patients are typically instructed to continue taking Jentadueto twice daily in 2.5 mg linagliptin/ 1000 metformin HCl doses.
Patients who are taking Jentadueto should have their blood sugar levels checked frequently.
