Warnings & Recalls for Lazanda
Seek emergency medical attention or Poison Help line at 1-800-222-1222 immediately if you overdose.
Overdosing can be fatal especially to a child.
Don't use a bottle of Lazanda that hasn't been used for 5 days or longer.
Do not give to anyone under 18 years old. Keep out of reach of children because the amount of fentanyl in each bottle can
be fatal to a child.
Lazanda is a habit forming drug and should only be used for the person it's prescribed for. Fentanyl can
impair your thinking and reactions so be sure to avoid driving or operating machinery until you know how Lazanda will affect you.
Do not drink alcohol with can increase drowsiness or cause breathing problems.
Drugs that may interact with Lazanda
Don't take Lazanda with any other narcotic pain medications, sedatives, tranquilizers, sleeping pills, muscle relaxers, or other medications that may make you sleepy or slow your breathing because there may be
dangerous side effects. Many drugs may interact with Lazanda be sure to tell your doctor if you are any medications such as:
- steroids such as prednisone and others
- modafinil (Progivil);
- HIV/AIDS medicine such as delavirdine (Rescriptor), efavirenz (Sustiva, Atripla), fosamprenavir (Lexiva), nevirapine (Viramune), ritonavir (Norvir, Kaletra), and others;
- pioglitazone (Actos, Actoplus Met, Duetact);
- seizure medication such as carbamazepine (Carbatrol, Tegretol), oxcarbazepine (Trileptal), phenytoin (Dilantin), and others; or
- St. John's wort;
- an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), rifabutin (Mycobutin), rifampin (Rifater, Rifadin, Rifamate), telithromycin (Ketek), and others;
- antifungal medication such as itraconazole (Sporanox), ketoconazole (Nizoral), miconazole (Oravig), or voriconazole (Vfend);
- heart or blood pressure medication such as diltiazem (Cartia, Cardizem), nicardipine (Cardene), quinidine (Quin-G), verapamil (Calan, Covera, Isoptin, Verelan), and others;
- aprepitant (Emend);
- phenobarbital (Solfoton) or other barbiturates;
Family planning
The FDA categorizes Lazanda as a pregnancy category C.
It may cause seizure, addiction, withdrawal symptoms and breathing problems for a newborn if the mother takes the medication during pregnancy. Be sure to tell your doctor immediately if you are pregnant or plan on becoming pregnant during treatment.
Lazanda may also cause drowsiness, breathing problems, or addiction and withdrawal symptoms in a nursing infant.
Do not breast feed while on Lazanda.
Lazanda Treatment and Use
What is Lazanda?
Lazanda is an opioid pain medication, also referred to as a narcotic. It’s only available under a special program called Lazanda REMS and must be registered within the program. Patients must sign documents stating that they understand the risks and benefits of using Lazanda Nasal Spray.
How does Lazanda work?
Lazanda Nasal spray is used to treat short-lived episodes of severe cancer pain only. Not for treating non-cancer related pain from surgery, dental work, or migraine headaches.
Dosage information
The usual starting dose is 1 single spray into 1 nostril. The dosage may change at your doctor’s discretion to make sure you get the best results. Do not treat more than 4 pain episodes per day with Lazanda. Inform your doctor immediatly if you have breakthrough pain more than 4 times in one day. Don’t stop taking Lazanda without your doctor advice and be sure to ask your doctor how to avoid withdrawal symptoms when you stop taking the medication.