Metoprolol Succinate Side Effects
Serious Adverse Reactions
There are
serious adverse reactions to taking
Metoprolol Succinate:
- shortness of breath
- wheezing
- swelling of the hands, feet, ankles, or lower legs
- unusual weight gain
- fainting
- rapid, pounding, or irregular heartbeat
Common Adverse Reactions
Other more common adverse reactions which are comparatively milder are:
- dizziness or lightheadedness
- tiredness
- depression
- nausea
- dry mouth
- stomach pain
- vomiting
- gas or bloating
- heartburn
- constipation
- rash or itching
- cold hands and feet
- runny nose
If you or a loved one have suffered serious adverse effects as a result of taking this drug, please do not hesitate to
contact someone who can help you.
Warnings & Recalls for Metoprolol Succinate
Black Box Warning
Following
abrupt discontinuation of therapy with this drug, there have been instances of exacerbations of chest pain and in many cases,
heart attacks. The dosage should be gradually reduced over a period of 1-2 weeks and the patient should be closely monitored while discontinuing therapy with
Metoprolol Succinate.
Warnings & Precautions
- Abrupt withdrawal from this drug in instances of coronary artery disease which can exacerbate angina pectoris or cause a heart attack
- Abrupt withdrawal from this drug can instigate a thyroid storm in patients with pre-existing thyroid conditions
- History of bronchospastic disease
- Diabetes mellitus which can lead to masked symptoms of hypoglycemia as well as tachycardia
- Heart failure rates may increase as dosages of this drug increase
- Preexisting hepatic function impairment
- Major noncardiac surgery upon initiation of high-dose extended release Metoprolol Succinate therapy. (Bradycardia, hypotension, stroke and death have been reported in patients with cardiovascular risk factors)
- Major surgery and anesthesia may increase risks of impaired ability of heart to respond to reflex adrenergic stimuli
- Preexisting peripheral vascular disease which can aggravate or cause symptoms of arterial insufficiency
- Pheochromocytoma which is associated with paradoxical increase in blood pressure when not first administered with an alpha-blocker
- Thyrotoxicosis which may mask clinical signs of hyperthyroidism such as tachycardia.
Contraindications
- Serious bradycardia
- Decompensated cardiac failure
- Cardiogenic shock
- 2nd and 3rd degree heart block
- Hypersensitivity to Metoprolol Succinate or any product component
- Sick sinus syndrome (without functioning permanent pacemaker)
Metoprolol Succinate Treatment and Use
Metoprolol Succinate is a selective β1 receptor blocker medication used in the treatment of diseases of the cardiovascular system, specifically hypertension. The active substance in Metoprolol Succinate is meant to be an extended-release form of Metoprolol Succinate, usually in a capsule form. Metoprolol Succinate is indicated for the treatment of angina, congestive heart failure, and hypertension. The off-label indications for Metoprolol Succinate are for heart attacks, atrial fibrillation, cardiac dysrhythmia, generalized atherosclerosis and for ischemic heart disease.
How Does Metoprolol Succinate Work?
Metropolol Succinate has selective activity on β-blocker receptors located mainly within cardiac muscles, reducing the strain on the heart and allowing it to pump more easily. At higher doses, it also inhibits β2 adrenoreceptors of bronchial and vascular smooth muscles.
Adverse Side Effects of Metoprolol Succinate
The most serious adverse side effect of this drug occurs in the respiratory system, and is a condition known as bronchospasm. The most common side effects of Metoprolol Succinate are often neurological side effects such as dizziness, fatigue, and headache.
Contact Someone Who Can Help You
If you or a loved one have suffered serious adverse effects as a result of taking this drug, please do not hesitate to contact someone who can help you.
