Pentasa Side Effects
Serious Adverse Side Effects
Pentasa | Mesalazine has many serious adverse side effects associated with it, such as:
- Cardiovascular side effects such as pericarditis, in which the sac-cover of the heart becomes inflamed
- Gastrointestinal side effects such as pancreatitis, in which the pancreas is inflamed, and rectal bleeding
- Hematological side effects such as agranulocytosis which is a failure of the bone marrow to make a sufficient amount of white blood cells, aplastic anemia which is a failure of the bone marrow to replenish new blood cells, leukopenia and neutropenia which are conditions of a decreased number of white blood cells, pancytopenia which is a deficiency of all types of blood cells, and thrombocytopenia which means low platelet count
- Hepatic side effects such as cholestatic hepatitis- which means that bile from the stomach cannot flow to the duodenum. May also cause chemical driven liver damage, and liver failure
- Immunological side effects such as a hypersensitivity reaction
- Renal side effects such as kidney failure
- Other side effects such as drug intolerance
Common Adverse Side Effects
Less severe and more common adverse side effects of
Pentasa | Mesalazine include:
- Gastrointestinal side effects such as abdominal pain, diarrhea, flatulence, nausea and upper abdominal pain
- Hepatic side effects such as abnormal liver function
- Neurological side effects such as headache
- Respiratory side effects such as the common cold
Warnings & Recalls for Pentasa
The chief contraindication of
Pentasa | Mesalazine is a hypersensitivity to Mesalamine, other salicylates including aspirin or any other component of
Pentasa | Mesalazine.
Who Should Not Use This Drug
Warnings, precautions and preexisting conditions that hinder a patient’s ability to take
Pentasa | Mesalazine include:
- Concurrent use with antacids
- Concurrent use of products that contain Mesalamine
- Elderly patients have a greater risk of blood disorders
- Liver disease
- Pyloric stenosis, which is a narrowing of the opening of the stomach to the small intestine
- History of kidney disorders
- History of sulfasalazine hypersensitivity
- History of sulfite hypersensitivity
Pentasa Treatment and Use
Pentasa | Mesalazine is a drug that is prescribed to treat active ulcerative colitis, a form of inflammatory bowel disease. It is known as an anti-inflammatory medication and is classified as a bowel-specific aminosalicylate, which acts in the gut and conducts predominant actions there. A derivative of salicylic acid, Pentasa | Mesalazine is also thought of as an antioxidant that reduces the activity of free radicals, which are a harmful byproduct of metabolism that contribute to the aging process. It is worth noting that this drug comes in tablet and capsule form to take orally.
Pentasa | Mesalazine has non-FDA labeled indications to treat:
How does Pentasa work?
The active ingredient “mesalamine” in Pentasa | Mesalazine diminishes any possible inflammation of the bowels by the inhibition of certain acidic metabolites. This component of the drug is also a scavenger of free radicals which are more pronounced in the patients who are prescribed this drug for relief from any diseases linked to the inflammation of the bowels.
Dosage
The manufacturers of Pentasa | Mesalazine have developed a new 500mg dosage of this drug to deliver more potential to combat symptoms that arise from inflammatory bowel disease.
Other Names for Pentasa
Brand Names
- Pentasa
- Canasa
- Rowasa
- Asacol
- Lialda
- Apriso
- Salofalk
Generic Name
Lawsuits & Legal Information for Pentasa
Author:
Partha Choudhury
Posted on Oct 10, 2012
