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Prinzide (Lisinopril and Hydrochlorothiazide)
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Prinzide (Lisinopril and Hydrochlorothiazide) Side Effects

The front and back of two Prinzide tablets.
Although uncommon, Prinzide may cause serious adverse side effects. If you experience any of these symptoms, contact your doctor immediately:
  • Angiodema, a swelling similar to hives which occurs beneath the surface of the skin and may inflame the eyes and mouth, while also causing difficulty breathing
  • Hyperkalemia or an elevated level of potassium may be caused by the use of Prinzide. Although typically only mild cases are reported, Hyperkalemia can affect the body in many ways including weakening muscles and causing irregular heart rythms. If left untreated, Hyperkalemia may even result in death.
  • Heart palpitations (irregular heartbeat)
  • Hypo-tension or low blood pressure often causing lightheadedness or fainting, also known medically as syncope
  • Allergic reactions such as rashes, itchiness and swelling of the tongue, face or throat causing troubled breathing
  • Signs of infection including fever, sore throat and chlls
  • Severe stomach and/or abdominal pain, and muscle cramps or weakness
  • Jaundice such as yellowing of the eyes and skin, and decrease in vision or pain in eyes which may be signs of future liver failure
  • Irregularity in urination such as a decrease in urination or darkened urine
  • Symptoms of low blood sodium including confusion or seizures
  While adjusting to Prinzide, common side effects  include:
  • Drowsiness and faintness
  • Dizziness
  • Headache
  • Dry coughing
  • Nausea