Prinzide (Lisinopril and Hydrochlorothiazide) Side Effects

The front and back of two Prinzide tablets.

Although uncommon, Prinzide may cause serious adverse side effects. If you experience any of these symptoms, contact your doctor immediately:

Angiodema, a swelling similar to hives which occurs beneath the surface of the skin and may inflame the eyes and mouth, while also causing difficulty breathing
Hyperkalemia or an elevated level of potassium may be caused by the use of Prinzide. Although typically only mild cases are reported, Hyperkalemia can affect the body in many ways including weakening muscles and causing irregular heart rythms. If left untreated, Hyperkalemia may even result in death.
Heart palpitations (irregular heartbeat)
Hypo-tension or low blood pressure often causing lightheadedness or fainting, also known medically as syncope
Allergic reactions such as rashes, itchiness and swelling of the tongue, face or throat causing troubled breathing
Signs of infection including fever, sore throat and chlls
Severe stomach and/or abdominal pain, and muscle cramps or weakness
Jaundice such as yellowing of the eyes and skin, and decrease in vision or pain in eyes which may be signs of future liver failure
Irregularity in urination such as a decrease in urination or darkened urine
Symptoms of low blood sodium including confusion or seizures

While adjusting to Prinzide, common side effects include:

Drowsiness and faintness
Dizziness
Headache
Dry coughing
Nausea

Warnings & Recalls for Prinzide (Lisinopril and Hydrochlorothiazide)

In June of 2012 the US Food and Drug Administration approved information about Prinzide as a black box warning indicating that this hypertension medication may cause harm or even death to developing fetus in expectant women.According to the FDA, Prinzide may lead variations in the renal function as the glomerular filtration rate (GFI) through the kidney may be altered or even cause the kidney to fail. Hydrochlorothiazide found in Prinzide may also cause acute transient myopia and acute angle-closure glaucoma.Before taking Prinzide, let your doctor know if you have:

Diabetes
Liver or heart disease
Kidney disease or kidney failure
A history of angiodemia
Pancreatitis
Asthma
High cholesterol
Any allergies to Prinzide or any angiotensin-converting enzyme inhibitors or preservative

Do not take Prinzide if you:

Are pregnant, planning on becoming pregnant, or are breastfeeding
Are on dialysis
Drink alcohol frequently
Will be undergoing anesthesia
Are taking Dofetilide or Ketanserin

If you are taking Prinzide check your blood pressure regularly and be aware of any abnormalities you may have.

Prinzide (Lisinopril and Hydrochlorothiazide) Treatment and Use

Prinzide | Lisinopril and Hydrochlorothiazide is an oral tablet produced by Merck and Company Inc. to be used in treating high blood pressure (hypertension) among patients. Prinzide includes a combination of two medications:

Lisinopril, an angiotensin-converting enzyme or “ACE” inhibitor which reduces high blood pressure. Lisinopril is commonly used to treat heart failure.
Hydrochlorothiazide, a diuretic ‘water pill’ used to remove excess fluids from the body.

How Does Prinzide Work?

Prinzide lowers blood pressure by loosening the width of blood vessels with the use of Lisinopril, allowing blood to flow more steadily throughout the body. This accounts for a more efficient flow of blood through the heart. Simultaneously, Hydrochlorothiazide reduces liquid retention by allowing the kidneys to remove excess water and salts from the body while depositing these unnecessary fluids into the urine.

Prinzide Dosage For High Blood Pressure

Either Prinzide 10mg/12.5mg or 20mg/12.5mg should be taken by mouth once daily or as prescribed by your doctor.
Dosage may fluctuate depending on the patients response to Prinzide or side effects due to this drug.
Patients with other medical conditions or patients who are taking other medications may be prescribed different dosages.
It may take many weeks to see full results in lowering blood pressure using Prinzide.

General Dosage For Prinzide

Prinzide is to be taken once daily by mouth with water and with or without food.
For optimal results, use Prinzide on a regular basis to maintain a more steady blood flow.
To work properly, take Prinzide as prescribed by your healthcare provider.
If a dose is missed, take Prinzide as soon as possible or continue with your next scheduled dose. Do not take more than one dose at a time.
Consult your doctor before ending usage of Prinzide.

Other Names for Prinzide (Lisinopril and Hydrochlorothiazide)

Brand Name:

Zestoric

Generic:

Lisinopril-hydrochlorothiazide