Trizivir Side Effects
Serious Side Effects of Trizivir
rapid heart rate, dizziness or faintness, difficulty concentrating- jaundice (yellowed skin or eyes), feeling itchy, loss of appetite, darkened urine, clay or pale colored stools which could be signs of liver damage
- pain or tension in the chest or spreading to the arm or shoulder
- abnormal bruising or bleeding
- strong pain in the upper stomach and back
- extreme pain in the lower back and loss of control over your bladder or bowel functions
- mouth sores
- changes in menstruation, inability to have sex, or lack of desire to have sex
- flu-like symptoms such as fever, chills, cough, and aching
- unexplained weight loss
- persistent diarrhea
- swelling of the neck or throat
- vision impairment, difficulty walking, balancing, breathing, speaking, or swallowing
- trouble sleeping
- increased sweating
- agitation, feeling nervous or anxious
- shaking or trembling of the hands
- rash or redness and irritation of the skin
- severe allergic reaction: swelling of the mouth, tongue, throat, lips, or face, trouble breathing, hoarseness, skin rash or hives
Trizivir and Lactic Acidosis
Trizivir may increase your
risk of developing
lactic acidosis. Patients who are
overweight, have problems with their
liver, are a
female,
or have used
HIV or AIDS medicines for an extended period of time may be more susceptible to this disease. If you have these symptoms, stop taking Trizivir and contact your doctor
right away:
- severe abdominal pain
- extreme tiredness
- irregular or dangerously high heart rate
- hyperventilating (rapid breathing)
- feeling anxious and nauseous
- loss of strength
Common Side Effects of Trizivir
- headache
- pain or aching in joints
- feeling depressed or anxious
- cold-like symptoms such as congestion, sneezing and pain in the sinuses
- nauseousness
- mild diarrhea
- changes in body fat distribution
Warnings & Recalls for Trizivir
Trizivir Black Box Warning
Trizivir has received a
black box warning due to a risk for the development of allergic reaction and
blood toxicity, which are potentially fatal side effects of some of the ingredients contained within Trizivir.
Trizivir and Pregnancy
Trizivir is an FDA
pregnancy Category C medicine. Research has not been conducted to confirm if Trizivir may harm the
fetus if taken during pregnancy.
If you have HIV or AIDS, do not breastfeed your child. This could pass the infection to your child. If you are
pregnant,
may become pregnant, or are
breastfeeding, ask your doctor if Trizivir is right for you.
If you have
human immunodeficiency virus (HIV), it is important to receive treatment to avoid passing the virus onto the newborn.
General Warnings
Patients using Trizivir who have
hepatitis B may be at an
increased risk for developing
liver damage and symptoms after ending treatment. Have your liver checked
regularly while taking Trizivir if you have hepatitis B.
Do not use Trizivir if you are
allergic to any ingredient in the medicine. To avoid further liver damage, patients with the following conditions
should not take Trizivir:
- liver disease or failure
- hepatitis B
- hepatitis C
To ensure that you may safely use Trizivir,
tell your doctor if you suffer from any of the following conditions:
- bone marrow suppression (myelotoxicity)
- kidney disease or failure
- heart problems or disease, or a higher risk for developing heart disease (including patients who smoke, have diabetes or have high cholesterol)
- high blood pressure (hypertension)
- any treatments for HIV you may have used
To ensure that Trizivir if safe and effective, patients should have
frequent blood tests and examinations.
Trizivir
does not prevent the spread of HIV from an infected person to their partner during sex.
Ask your doctor about safe ways to prevent transmission.
Do not share toothbrushes or razors you have used if you have HIV.
Patients who take Trizivir in high doses or for a long amount of time are at greater
risk for developing
lactic acidosis. See "
Side Effects" tab for information about this
life-threatening disease.
Trizivir Interactions
Limit your use or
avoid drinking alcohol while taking Trizivir. Patients who drink often during treatment are more likely to suffer from
liver damage.
Do not use any of the following
HIV treatments while taking Trizivir and ask your doctor about medicines which may be safely used:
- Atripla
- Combivir
- Complera
- Emtriva
- Epivir
- Epzicom
- Retrovir
- Truvada
- Zerit
- Ziagen
Let your doctor know about any prescription or non-prescription medicines you are using. The following drugs
may interact with Trizivir:
- antivirals
- methadone (moderate to severe pain reliever)
- cancer treatments
- interferon
- sulfa drugs (sulfonamide medicines which treat bacterial and some fungal infections)
Trizivir Treatment and Use
Trizivir | abacavir, lamivudine, and zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI) marketed by Viiv Healthcare and approved by the U.S. Food and Drug Administration in 2000 for treating human immunodeficiency virus (HIV). Trivizir may also be prescribed to prevent the development of acquired immunodeficiency syndrome (AIDS) in patients who suffer from HIV.
Trizivir does not cure or prevent the transmission of HIV or AIDS.
Trizivir should not be used by adolescents with HIV who weigh under 90 lbs.
How Does Trizivir Work?
Trizivir works through the combination of abacavir, lamivudine, and zidovudine. Normally, the HIV virus attacks cells in the body as it converts RNA to DNA. Trizivir stops the virus from infecting DNA cells. This prevents further spread of human immunodeficiency virus (HIV) throughout the body.
Trizivir Dosage Information
Trizivir comes in tablet form to be taken by mouth. Trizivir should be taken only as prescribed by your doctor. Do not take more or less of this medication than recommended. Typically, Trizivir is taken twice each day, once in the morning and once in the evening, with or without food. Take Trizivir around the same time each day to ensure effectiveness.
Do not end treatment with Trizivir unless your doctor directs you to do so. Be sure to use all medicines prescribed to you for your treatment.
