Wellbutrin | bupropion hydrochloride is an atypical, non tricyclic antidepressant that differs from other commonly prescribed mood-enhancing medications such as selective serotonin reuptake inhibitors (SSRI’s). Wellbutrin is manufactured by GlaxoSmithKline, though generic bupropion is made by several other drug makers.
Wellbutrin is a norepinephrine and dopamine reuptake inhibitor (NDRI). This pharmacological action is believed to relieve depression in those treated with Wellbutrin. Currently, bupropion containing drugs such as Wellbutrin, Zyban and Chantix (a smoking-cessation aid), are the only FDA approved NDRI’s.
After your mental health professional or primary care physician (in some cases) decides that you are a candidate for Wellbutrin, he or she will make a dosing recommendation based on your individual medical history as well as your age, weight, and the extent to which your condition affects you.
Wellbutrin comes in oral tablet form and is taken two to four times daily, or in a once daily formula. Although many factors contribute to an individual’s physician-recommended dosage, the usual starting dose of Wellbutrin is 100mg, twice daily. Each individual dose of this medication should not exceed 150 mg (to avoid seizures), and maximum daily dose should never go over 450 mg in a 24 hour period. Doing this may raise your risk of seizure or other serious complications.